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We have reached yet another landmark: ResearchGATE is excited to announce that 20,000 members have signed up in total! This massive growth within just seven months of operation makes us very happy. We take this as a motivation to further improve our tools and features, turning the platform into your gate to an entire world of science. True cooperation across borders and disciplines seems to become a reality.
With every researcher joining, the network becomes more interesting and diverse. So please continue to invite fellow scientists, colleagues and friends to ResearchGATE! Thank you for your support Tuesday, December 16. 2008 Microvesicles from tumours triggering tumour growth and angiogenesisPosted by in NewsComments (0) | Trackbacks (0)
Glioblastoma, a form of metastatic brain cancer with poor prognosis, has been highlighted again by Skog et. al. for the formation of Micorvesicles. These microvesicles, or exosomes, are secereted by the tumor into the serum and contain mRNA, miRNAs and certain proteins. The mRNAs encode different genes, one of which is an oncogenic form of the growth factor receptor, EGFR. Proteins contained within the vesicles also trigger tumor growth of glioblastomas, tubule formation in vascular endothelial cells and micro RNAs. These microvesicles are detectable in the serum of patients, and could potentially lead to a more specific diagnostic biomarker for treatment options. Full details can be found at Nature Cell biology
Friday, December 12. 2008 Rate published papers and write commentsPosted by ResearchGate Team in FeaturesComments (0) | Trackbacks (0) ResearchGATE just implemented a new feature: From now on, every scientfic paper accessible via our search engines can be rated and commented by ResearchGATE members. This unique tool creates a new way of discussing and sharing research results within the scientific community. Moreover, it will allow you to find important, high-ranking and ground-breaking papers more easily. Since our publication database of more than 30 million documents is updated daily, you can rate even the most recent publications.
Monday, December 8. 2008 Viral recognition by the hostPosted by in NewsComment (1) | Trackbacks (0)
There are many different aspects to innate immunity, but one of the most advanced fields of research by far is the recognition of viral nucleic acids by the host. Several papers have recently identified either key components of signalling pathways (e.g. the identification of STING/MITA/MPYS as part of RIG-I signalling 1,2,3) or new sensors for DNA recognition (e..g DAI 4, 5 ). These recent advances have changed the field and opened up the area, allowing further research into identifying new sensors or characterisation of the common signalling pathway (TBK1/IRF3 & IFN) used by most of these molecules. A recent in-depth review by Unterholzner & Bowie covers all methods of host response in regards to pattern recognition receptors (or PRRs as they are known). This review is definitely the most comprehensive by far and has done well to remain up to date.
Sunday, December 7. 2008 Expand your libraryPosted by ResearchGate Team in FeaturesComments (0) | Trackbacks (0) Creating and expanding your ResearchGATE library has become even easier: Import your articles by using the following data types: BibTex, RIS, Endnote, Reference Manager files. If you know another important library format, please let us now. Thank you for having provided us with the idea to devleop this feature!
We often get feedback from users saying that they found papers through the ResearchGATE search engine they had been searching for a long time. Since ResearchGATE’s mission is the promotion of collaboration and the distribution of knowledge, we now introduced a new feature:
Whenever you find a paper you consider interesting to a fellow researcher, simply click on “Suggest”. ![]() You will then be taken to a new screen, where you can select the researchers you want to suggest this paper to. ![]() Wednesday, December 3. 2008 Why some cancer cells survive chemotherapyPosted by in NewsComments (0) | Trackbacks (0)
In its current issue, Science magazine published the results of a childhood leukemia study carried out at St. Jude Children's Research Hospital in Mephis (Tennessee). Based on 61 samples from young patients that relapsed backed into the diesease after seemingly succesful chemotherapy, they found that in the majority of cases, a loss in DNA "caused certain genes to shut down". While the results might not necessarily be transferable to other types of cancer, they seem to indicate a path towards preventing relapse and identifyig children at risk.
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